Suna ƙirƙirar 3D ƙaramin ƙwaƙwalwa don nazarin halayen ƙwayoyin cuta

neurons

A yau ina so in gabatar muku da aikin da injiniyan Mexico ya yi Rodrigo lozano, dalibi na digiri na uku a Jami'ar Wollongong (Ostiraliya) wanda ya sami damar tsarawa da kuma kirkira ta hanyar buga 3D ba komai ba sai karamar kwakwalwa wacce za a iya nazarin halayyar jijiyoyin wasu cututtukan kwakwalwa ko kuma na mutanen da ke amfani da kwayoyi.

Don aiwatar da gwaje-gwajen farko kan wannan rikitaccen aikin, da alama injiniyan ya yanke shawara ƙirƙirar ƙaramin samfurin kwakwalwa ta amfani da ɗab'in 3D da fasahar ƙira. A saman sa, an sanya jijiyoyin beraye akan layuka daban-daban na samfurin wanda yayi nasarar rayuwa har tsawon kwanaki goma yana aiwatar da duk hanyoyin sadarwar su kuma da alama baya fama da wata illa.

Suna ƙirƙirar ƙaramin kwakwalwa inda ƙananan ƙwayoyi zasu iya rayuwa har tsawon kwanaki 10 suna yin duk ayyukansu na al'ada.

Kamar yadda ya bayyana da nasa Rodrigo lozano:

Neuananan ƙananan ƙwayoyin cuta daga berayen embryonic an lulluɓe su a cikin wani polymer hydrogel da ake kira gellan gua, wanda asalinsa ne kuma yana ba da damar ƙirƙirar dakatar da ƙwayoyin da ake kira 'tawada-tawada'

Game da kayan da aka gaya mana a baya, ya kamata a lura cewa wannan daga low cost y dace da jikin mutum tunda ya isa ya bar abubuwan gina jiki da kayan asirin da kwayoyin kansu suka kirkira su shiga cikinsa. Hakanan, wannan kayan yana da dukiyar da yake karfafa shi sosai a yanayin zafin jiki yayin gabatar da kayan aikin cewa za'a iya canza shi ta hanyar kemikal tare da peptides kamar abin da ake kira RGD.

A matsayin cikakken bayani na karshe, yi tsokaci akan godiyar tsarin wannan karamin kwakwalwa da kuma amfani da wannan sabon hydrogel ƙananan ƙwayoyin cuta sun sami haɓaka kuma suna haɓaka haɗin su zuwa ɗaruruwan microns. Godiya ga wannan, bayan kwana goma daga farkon gwajin, an gano cewa tsarin yana da halaye iri ɗaya a cikin ƙwayoyin ƙwayoyin halitta masu girma har ma da ma jijiyoyin sun gudanar da ƙirƙirar shimfidar layuka kwatankwacin ƙwaƙwalwar ƙwaƙwalwar.


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