Namuhla ngifuna ukukunikeza umsebenzi owenziwe ngunjiniyela waseMexico URodrigo lozano, umfundi wamanje wobudokotela e-University of Wollongong (Australia) okwazile ukuklama nokukhiqiza nge-3D ukuphrinta okungaphansi kobuchopho obuncane lapho afunda khona ngokuziphatha kwama-neuron wezifo ezithile zobuchopho noma kwabantu abasebenzisa izidakamizwa.
Ukwenza ucwaningo lokuqala kule phrojekthi eyinkimbinkimbi, ngokusobala unjiniyela wanquma dala imodeli yobuchopho encane usebenzisa ubuchwepheshe be-3D bokuphrinta nokwakha. Kuyo, ama-neurons wamagundane abekwa ezingxenyeni ezahlukahlukene zemodeli ezikwazile ukusinda izinsuku eziyishumi zisebenzisa zonke izinqubo zazo zokuxhumana futhi ngokusobala zingatholi monakalo.
Bakha ubuchopho obuncane lapho ama-neurons angaphila kuze kube yizinsuku eziyi-10 enza yonke imisebenzi yawo yemvelo.
Njengoba kuchazwe ngabakwakho URodrigo lozano:
Ama-cortical neurons angavuthiwe avela kumagundane embryonic afakwe kwi-polymer hydrogel ebizwa nge-gellan gua, engokwemvelo futhi evumela ukudala ukumiswa kwamaseli abizwa ngokuthi 'i-bio-ink'
Mayelana nezinto esitshelwe kuzo ngaphambilini, kufanele kuqashelwe ukuthi lokhu kuvela izindleko eziphansi y iyahambisana nomzimba womuntu ngoba inesibindi ngokwanele ukuvumela izakhi zomzimba kanye nemfucuza eyakhiwe ngamaseli uqobo ukuthi idlule kuyo. Futhi, le nto inesakhiwo esiqinisa kahle ekamelweni lokushisa ngenkathi iletha indawo ukuthi ingashintshwa ngamakhemikhali ngama-peptide afana nalawo abizwa nge-RGD.
Njengemininingwane yokugcina, phawula ukuthi ngenxa yesakhiwo salokhu ubuchopho obuncane nokusetshenziswa kwalokhu okusha i-hydrogel ama-neurons akwazi ukukhula nokukhulisa ukuxhumana kwawo namakhulu ama-microns. Ngenxa yalokhu, ngemuva kwezinsuku eziyishumi kusukela ekuqaleni kokuhlolwa, kwatholakala ukuthi isakhiwo sinezici ezifanayo kumaseli we-cortical avuthiwe nokuthi ama-neurons akwazi ukwakha izakhiwo ezinamatshe afana ne-cerebral cortex.